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Rose continues to develop personalised approaches to smoking cessation remedy based on smokers’ characteristics, including degree of nicotine dependence, and genomic markers, which he helped to establish in the first genome-huge association research of smoking cessation therapy consequence. The first factor is "titer", which refers to the variety of antibodies present, and the second factor is the "affinity" of the anti-nicotine antibody to the nicotine.

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